Institutions
Pierre-Marie Lledo
Perception and Memory
CNRS URA 2182 - Institut Pasteur
25, rue du Docteur Roux
75015 Paris
Tel +331 4568 8803
Fax +331 4568 8369
We are investigating the functional meaning of adult neurogenesis forsensory and cognitive functions. Methodologically, this include morphological, molecular and electrophysiological characterization of new neurons in vitro and in vivo as well as behavioural approaches to investigate the impact of adding new neurons to pre-existing circuits. Special emphases are given to investigate the relative contribution of intrinsic (genetic) and extrinsic (epigenetic) cues regulating this process using genetically manipulated rodents and different environmental paradigms.